Paper

M. Kih§, E.J. Lee§, N.K. Lee, Y.K. Kim, K.E. Lee, C. Jeong, Y. Yang, D-H. Kim, I.-S. Kim*. Designed trimer-mimetic TNF superfamily ligands on self-assembling nanocages. Biomaterials 180, 67-77 (2018) (§ Co-First Author.) IF: 8.806. JCR Ranking %: 1.28

H.J. Kim, J. Huh, Y.W. Kwon, D. Park, Y. Yu, Y. E. Jang, B.-R. Lee, E. Jo, E.J. Lee, Y. Heo, W. Lee & J. Lee*. Biological conversion of methane to methanol through genetic reassembly of native catalytic domains. Nature Catalysis 2, 342–353 (2019)

제목 1

E.J. Lee*. Recent advances in protein-based nanoparticles. Korean Journal of Chemical Engineering 35, 1765–1778 (2018) 

G.H. Nam§, E.J. Lee§, Y.K. Kim, Y. Hong, Y. Choi, M.J. Ryu, J. Woo, Y. Cho, D.J. Ahn, Y. Yang, I.C. Kwon, S.Y. Park*, and I.S. Kim*. Combined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer. Nature Communications 9, 2165 (2018). (§ Co-First Author.) IF: 12.353. JCR Ranking %: 4.69

E.J. Lee§, G.H. Nam§, N.K. Lee, M. Kih, E. Koh, Y.K. Kim, Y. Hong, S. Kim, S.Y. Park, C. Jeong, Y. Yang, and I.S. Kim*. Nanocage-Therapeutics Prevailing Phagocytosis and Immunogenic Cell Death Awakens Immunity against Cancer. Advanced Materials 30, 1705581 (2018). (§ Co-First Author.) IF: 21.950. JCR Ranking %: 1.36

N.K. Lee§, E.J. Lee§, S. Kim, G.H. Nam, M. Kih, Y. Hong, C. Jeong, Y. Yang, Y. Byun, I.S. Kim*. Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics. Journal of Controlled Release. 267, 172 (2017). (§ Co-First Author.) IF: 7.877. JCR Ranking %: 3.45.

K.C. Kwon, E. Jo, Y-W. Kwon, J.H. Ryu, E.J. Lee, K. Kim, and J. Lee. Superparamagnetic Gold Nanoparticles Synthesized on Protein Particle Scaffolds for Cancer Theragnosis. Advanced Materials 29, 1701146 (2017). IF: 21.950. JCR Ranking %: 1.36

M.S Huh§, E.J. Lee§, H. Koo, J.Y. Yhee, K.S. Oh, S. Son, S. Lee, S.H. Kim, I.C. Kwon, and K. Kim*. Polysaccharide-based Nanoparticles for Gene Delivery. Topics in current chemistry. 375, 31 (2017). (§ Co-First Author.) 

E. Koh, E.J. Lee, G.H. Nam, Y. Hong, E. Cho, Y. Yang*, and I.S. Kim*. Exosome-SIRPα, a CD47 blockade increases cancer cell phagocytosis. Biomaterials. 121, 121 (2017). IF: 8.806. JCR Ranking %: 1.28.

K.C. Kwon, H.K. Ko, J. Lee, E.J. Lee, K. Kim*, and J. Lee*. Enhanced in vivo tumor detection by active tumor cell targeting using multiple tumor receptor-binding peptides presented on genetically engineered ferritin nanoparticles. Small. 12, 4241 (2016). IF: 9.598. JCR Ranking %: 6.85

E.J. Lee, N.K. Lee, and I.S. Kim*. Bioengineered protein-based nanocage for drug delivery. Advanced Drug Delivery Reviews. 106, 157 (2016). IF: 13.660. JCR Ranking %: 1.15

H.J. Kim, E.J. Lee, J.S Park, S.J. Sim, and J. Lee* Reversible and multi-cyclic protein–protein interaction in bacterial cellulosome-mimic system using rod-shaped viral nanostructure. Journal of Biotechnology. 221, 101-106 (2016). 

E.J. Lee, S.J. Lee, Y.S. Kang, J.H. Ryu, K.C. Kwon, E. Jo, J.Y. Yhee, I.C. Kwon,  K. Kim*, and J. Lee*. Engineered proteinticles for targeted delivery of siRNA to cancer cells. Advanced Functional Materials 25, 1279 (2015). IF: 13.325. JCR Ranking %: 4.11

E.J. Lee§, E. Lee§, H.J. Kim, J.H. Lee, K.Y. Ahn, J.S. Park, and J. Lee*. Self-assembled Proteinticle Nanostructures for 3-dimensional Display of Antibodies. Nanoscale 6, 14919 (2014). (§ Co-First Author.) IF: 7.233. JCR Ranking %: 10.27

K.C. Kwon, J.H. Ryu, J.H. Lee, E.J. Lee, I.C. Kwon, K. Kim*, and J. Lee*. Proteinticle/Gold Core/Shell Nanoparticles for Targeted Cancer Therapy without Nanotoxicity. Advanced Materials 26, 6436 (2014). IF: 21.950. JCR Ranking %: 1.36

K.Y. Ahn, H.K. Ko, B.R. Lee, E.J. Lee, J.H. Lee, Y. Byun, I.C. Kwon, K. Kim*, and J. Lee*. Engineered protein nanoparticles for in vivo tumor detection. Biomaterials. 83, 5834 (2014). IF: 8.806. JCR Ranking %: 1.28.

D.S. Lee§, J.S Park§, E.J. Lee§, H.J. Kim, and J. Lee*. A protein nanofiber hydrogel for sensitive immunoassays. Analyst 138, 4786 (2013). (§ Co-First Author.) Back Cover. 

J.H. Lee, H.S. Seo, J.A. Song, K.C. Kwon, E.J. Lee, H.J. Kim, E.B. Lee, Y.J. Cha, and J. Lee*. Proteinticle Engineering for Accurate 3D Diagnosis. ACS Nano 7, 10879 (2013). IF: 13.709. JCR Ranking %: 4.21

E.J. Lee, K.Y. Ahn, J.H. Lee, J.S. Park, J.A. Song, S.J. Sim, E.B. Lee, Y.J. Cha, and J. Lee*. A novel bioassay platform using ferritin based nanoprobe hydrogel. Advanced Materials 49, 4739 (2012). Inside front cover. IF: 21.950. JCR Ranking %: 1.36

J.S. Park§, M.K. Cho§, E.J. Lee§, K.Y. Ahn, K.E. Lee, J.H. Jung, Y. Cho, S.S. Han, Y.K. Kim*, and J. Lee*. A highly sensitive and selective diagnostic assay based on virus nanoparticles. Nature Nanotechnology. 4, 259 (2009). (§ Co-First Author.) Highlighted in News & Views in the same issue of Nature Nanotechnology. IF: 37.490. JCR Ranking %: 1.40

Patent

International Patents

Registration

Protein nanoparticle based hydrogel.

- USA, Patent No. 10,001,477(18.06.19)

 

Chimeric protein, method for manufacturing the same, nano-sensor in which the chimeric protein is fixed, protein is fixed, and application thereof.

- USA, Patent No. 8,586,370(13.11.19)

Application

A novel anti-cancer fusion protein and use thereof.

- PCT No. PCT/KT2019/002531 (19.03.05)

 

Protein nanocage and an application thereof.

- USA, Application No. 16/247,937 (19.01.15)

- PCT No. PCT/KR2017/007679 (17.07.17)

 

A novel antitumor agent using exosome.

- PCT No. PCT/KR2017/015784 (17.07.17)

- USA, Application No. 16/475,052 (19.06.28)

- Japan, Application No. 2019-534796 (19.06.25)

- Europe, Application No. 17888530.7 (17.12.29)

 

Use of protein nanoparticle based hydrogel.

- USA, Application No. 13/938,575 (13.07.10)

 

Nanohair structure and an application thereof.

- USA, Application No. 14/189,552 (14.02.25)

- PCT No. PCT/KR2008/005256 (10.03.05)

 

Chimeric protein, method for manufacturing the same, nano-sensor in which the chimeric protein is fixed, protein is fixed, and application thereof.

- PCT No. PCT/KR2010/000640 (10.02.02)

 

Preparation method of recombinant protein by use a fusion expression partner.

- USA, Application No. 13/108,518 (11.05.16)

- PCT No. PCT/KR2008/005256 (08.09.05)

 

Domestic Patents

Registration

Protein nanocage and an application thereof.

- Patent No. 10-1953617-0000 (19.02.25)

Use of Protein nanoparticle based hydrogel.

- Patent No. 10-1721050 (17.03.23)

Protein nanoparticle based hydrogel.

- Patent No. 10-1660825 (16.09.22)

A chimeric protein, a preparation method thereof, a nanosenser fixed with the same and an application thereof.

- Patent No. 10-1309560 (13.09.11)

A chimeric protein, a preparation method thereof, a nanosenser fixed with the same and an application thereof.

- Patent No. 10-1267260 (13.05.20)

A nanohair structure and an application thereof.

- Patent No. 10-1163535 (12.07.02)

A preparation method of solubility recombinant protein by use of chemotaxis protein cheZ as a fusion expression partner.

- Patent No. 10-1077611 (11.10.21)

A preparation method of solubility recombinant protein by use of bacterioferritin as a fusion expression partner.

- Patent No. 10-1077612 (11.10.21)

A preparation method of solubility recombinant protein by use of putative HTH-type transcriptional regulator yjdC as a fusion expression partner.

- Patent No. 10-1077613 (11.10.21)

A preparation method of solubility recombinant protein by use of aspartate carbamoyl transferase catalytic chain as a fusion expression partner.

- Patent No. 10-1023518 (11.03.11)

Preparation method of recombinant protein by use of malate dehydrogenase as a fusion expression partner.

- Patent No. 10-0890183 (09.03.17)

Preparation method of recombinant protein by use of SlyD as a fusion expression partner.

- Patent No. 10-0890184 (09.03.17)

Preparation method of recombinant protein by use of Crr as a fusion expression partner.

- Patent No. 10-0890185 (09.03.17)

Preparation method of recombinant protein by use of RpoS as a fusion expression partner.

- Patent No. 10-0890186 (09.03.17)

A preparation method of solubility recombinant protein by use of Tsf as a fusion expression partner.

- Patent No. 10-0890187 (09.03.17)

A preparation method of solubility recombinant protein by use of PotD as a fusion expression partner.

- Patent No. 10-0890188 (09.03.17)

Preparation method of recombinant protein by use of RNA polymerase α subunit as a fusion expression partner.

- Patent No. 10-0890189 (09.03.17)

Application

A novel anti-cancer fusion protein and use thereof.

- Application No. 10-2018-0026230 (18.03.06)

Protein nanocage and an application thereof.

- Application No. 10-2017-0090608 (17.07.17)

Ferritin nanocage with increased half-life.

- Application No. 10-2017-0090319 (16.07.17)

A novel antitumor agent using exosome.

- Application No. 10-2016-0182573 (16.12.29)

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