Paper
S.A. Kim§, Y. Lee§, Y. Ko§, S. Kim, G.B. Kim, N.K. Lee, W. Ahn, N. Kim, G.-H. Nam, E.J. Lee*, and I.-S. Kim*. Protein-based nanocages for vaccine development, Journal of Controlled Release. 353, 767 (2023) IF: 11.467
S.A. Kim§, S. Kim§, G.B. Kim§, J. Goo, N. Kim, Y. Lee, G.-H. Nam, S. Lim, T. Kim, K.H. Chang, T.G. Lee, I.-S. Kim*, and E.J. Lee*, A Multivalent Vaccine Based on Ferritin Nanocage Elicits Potent Protective Immune Responses against SARS-CoV-2 Mutations, International Journal of Molecular Sciences. 23, 6123 (2022) IF: 6.208
J.S. Cho§, H.J. Oh§, Y.E. Jang§, H.J. Kim, A. Kim, J.-A. Song, E.J. Lee*, and J. Lee*, Synthetic pro-peptide design to enhance the secretion of heterologous proteins by Saccharomyces cerevisiae. Microbiologyopen 11, e1300 (2022) IF: 3.904
H.-D. Sung, N. Kim, Y. Lee and E.J. Lee*, Protein-based nanoparticle vaccines for SARS-CoV-2, International Journal of Molecular Sciences, 22, 13445. (2021) IF : 5.923
N.K. Lee, J.U. Choi, HR Kim, S.W. Chung, Y.G. Ko, Y.S. Cho, S.J. Park, E.J. Lee, S.Y. Kim, I.S. Kim, and Byun Y*. Caspase-cleavable peptide-doxorubicin conjugate in combination with CD47-antagonizing nanocage therapeutics for immune-mediated elimination of colorectal cancer, Biomaterials, 277, 121105. (2021).
Y. Choi, G.-H. Nam, G. Kim, S. Kim, Y.K. Kim, S.A. Kim, E.J. Lee* & I.-S. Kim* Nanocages displaying SIRP gamma clusters combined with pro-phagocytic stimulus of phagocytes potentiate anti-tumor immunity, Cancer Gene Therapy, 28, 960–970 (2021). IF: 5.987
G.B. Kim, H.-D. Sung, G.-H. Nam, W. Kim, S. Kim, D. Kang, E.J. Lee* & I.-S. Kim* Design of PD-1-decorated nanocages targeting tumor-draining lymph node for promoting T cell activation. Journal of Controlled Release, 333, 328-338 (2021)
H. Je, G.H. Nam, G.B. Kim, W. Kim, S.R. Kim, I.-S. Kim* & E.J. Lee* Overcoming therapeutic efficiency limitations against TRAIL-resistant tumors using re-sensitizing agent-loaded trimeric TRAIL-presenting nanocages. Journal of Controlled Release, 331, 7-18 (2021).
D. Jeong, H. Park, B.-K. Jang, Y.B. Ju, M.H. Shin, E.J. Oh, E.J. Lee & S.R. Kim* Recent advances in the biological valorization of citrus peel waste into fuels and chemicals, Bioresource Technology, 323, 124603 (2021).
W. Ahn, J.H. Lee, S.R. Kim, J. Lee* & E.J. Lee* Designed Protein- and Peptide-based Hydrogels for Biomedical Sciences, Journal of Materials Chemistry B, 9, 1919-1940 (2021).
D. Jeong, E.J. Oh, J.K. Ko, J.-O. Nam, H.-S. Park, Y.-S. Jin, E.J. Lee* & S.R. Kim* Metabolic engineering considerations for the heterologous expression of xylose-catabolic pathways in Saccharomyces cerevisiae, PLoS One. 15, e0236294 (2020).
H.J. Kim, J. Huh, Y.W. Kwon, D. Park, Y. Yu, Y. E. Jang, B.-R. Lee, E. Jo, E.J. Lee, Y. Heo, W. Lee & J. Lee*. Biological conversion of methane to methanol through genetic reassembly of native catalytic domains. Nature Catalysis 2, 342–353 (2019)
M. Kih§, E.J. Lee§, N.K. Lee, Y.K. Kim, K.E. Lee, C. Jeong, Y. Yang, D-H. Kim, I.-S. Kim*. Designed trimer-mimetic TNF superfamily ligands on self-assembling nanocages. Biomaterials 180, 67-77 (2018) (§ Co-First Author.) IF: 8.806. JCR Ranking %: 1.28
제목 1
E.J. Lee*. Recent advances in protein-based nanoparticles. Korean Journal of Chemical Engineering 35, 1765–1778 (2018)
G.H. Nam§, E.J. Lee§, Y.K. Kim, Y. Hong, Y. Choi, M.J. Ryu, J. Woo, Y. Cho, D.J. Ahn, Y. Yang, I.C. Kwon, S.Y. Park*, and I.S. Kim*. Combined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer. Nature Communications 9, 2165 (2018). (§ Co-First Author.) IF: 12.353. JCR Ranking %: 4.69
E.J. Lee§, G.H. Nam§, N.K. Lee, M. Kih, E. Koh, Y.K. Kim, Y. Hong, S. Kim, S.Y. Park, C. Jeong, Y. Yang, and I.S. Kim*. Nanocage-Therapeutics Prevailing Phagocytosis and Immunogenic Cell Death Awakens Immunity against Cancer. Advanced Materials 30, 1705581 (2018). (§ Co-First Author.) IF: 21.950. JCR Ranking %: 1.36
N.K. Lee§, E.J. Lee§, S. Kim, G.H. Nam, M. Kih, Y. Hong, C. Jeong, Y. Yang, Y. Byun, I.S. Kim*. Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics. Journal of Controlled Release. 267, 172 (2017). (§ Co-First Author.) IF: 7.877. JCR Ranking %: 3.45.
K.C. Kwon, E. Jo, Y-W. Kwon, J.H. Ryu, E.J. Lee, K. Kim, and J. Lee. Superparamagnetic Gold Nanoparticles Synthesized on Protein Particle Scaffolds for Cancer Theragnosis. Advanced Materials 29, 1701146 (2017). IF: 21.950. JCR Ranking %: 1.36
M.S Huh§, E.J. Lee§, H. Koo, J.Y. Yhee, K.S. Oh, S. Son, S. Lee, S.H. Kim, I.C. Kwon, and K. Kim*. Polysaccharide-based Nanoparticles for Gene Delivery. Topics in current chemistry. 375, 31 (2017). (§ Co-First Author.)
E. Koh, E.J. Lee, G.H. Nam, Y. Hong, E. Cho, Y. Yang*, and I.S. Kim*. Exosome-SIRPα, a CD47 blockade increases cancer cell phagocytosis. Biomaterials. 121, 121 (2017). IF: 8.806. JCR Ranking %: 1.28.
K.C. Kwon, H.K. Ko, J. Lee, E.J. Lee, K. Kim*, and J. Lee*. Enhanced in vivo tumor detection by active tumor cell targeting using multiple tumor receptor-binding peptides presented on genetically engineered ferritin nanoparticles. Small. 12, 4241 (2016). IF: 9.598. JCR Ranking %: 6.85
E.J. Lee, N.K. Lee, and I.S. Kim*. Bioengineered protein-based nanocage for drug delivery. Advanced Drug Delivery Reviews. 106, 157 (2016). IF: 13.660. JCR Ranking %: 1.15
H.J. Kim, E.J. Lee, J.S Park, S.J. Sim, and J. Lee* Reversible and multi-cyclic protein–protein interaction in bacterial cellulosome-mimic system using rod-shaped viral nanostructure. Journal of Biotechnology. 221, 101-106 (2016).
E.J. Lee, S.J. Lee, Y.S. Kang, J.H. Ryu, K.C. Kwon, E. Jo, J.Y. Yhee, I.C. Kwon, K. Kim*, and J. Lee*. Engineered proteinticles for targeted delivery of siRNA to cancer cells. Advanced Functional Materials 25, 1279 (2015). IF: 13.325. JCR Ranking %: 4.11
E.J. Lee§, E. Lee§, H.J. Kim, J.H. Lee, K.Y. Ahn, J.S. Park, and J. Lee*. Self-assembled Proteinticle Nanostructures for 3-dimensional Display of Antibodies. Nanoscale 6, 14919 (2014). (§ Co-First Author.) IF: 7.233. JCR Ranking %: 10.27
K.C. Kwon, J.H. Ryu, J.H. Lee, E.J. Lee, I.C. Kwon, K. Kim*, and J. Lee*. Proteinticle/Gold Core/Shell Nanoparticles for Targeted Cancer Therapy without Nanotoxicity. Advanced Materials 26, 6436 (2014). IF: 21.950. JCR Ranking %: 1.36
K.Y. Ahn, H.K. Ko, B.R. Lee, E.J. Lee, J.H. Lee, Y. Byun, I.C. Kwon, K. Kim*, and J. Lee*. Engineered protein nanoparticles for in vivo tumor detection. Biomaterials. 83, 5834 (2014). IF: 8.806. JCR Ranking %: 1.28.
D.S. Lee§, J.S Park§, E.J. Lee§, H.J. Kim, and J. Lee*. A protein nanofiber hydrogel for sensitive immunoassays. Analyst 138, 4786 (2013). (§ Co-First Author.) Back Cover.
J.H. Lee, H.S. Seo, J.A. Song, K.C. Kwon, E.J. Lee, H.J. Kim, E.B. Lee, Y.J. Cha, and J. Lee*. Proteinticle Engineering for Accurate 3D Diagnosis. ACS Nano 7, 10879 (2013). IF: 13.709. JCR Ranking %: 4.21
E.J. Lee, K.Y. Ahn, J.H. Lee, J.S. Park, J.A. Song, S.J. Sim, E.B. Lee, Y.J. Cha, and J. Lee*. A novel bioassay platform using ferritin based nanoprobe hydrogel. Advanced Materials 49, 4739 (2012). Inside front cover. IF: 21.950. JCR Ranking %: 1.36
J.S. Park§, M.K. Cho§, E.J. Lee§, K.Y. Ahn, K.E. Lee, J.H. Jung, Y. Cho, S.S. Han, Y.K. Kim*, and J. Lee*. A highly sensitive and selective diagnostic assay based on virus nanoparticles. Nature Nanotechnology. 4, 259 (2009). (§ Co-First Author.) Highlighted in News & Views in the same issue of Nature Nanotechnology. IF: 37.490. JCR Ranking %: 1.40
Patent
International Patents
Registration
Nanocage and use thereof
- USA, Patent No. 10,905,774(21.02.02)
Use of Protein nanoparticle based hydrogel.
- USA, Patent No. 10,001,477(18.06.19)
Chimeric protein, method for manufacturing the same, nano-sensor in which the chimeric protein is fixed, protein is fixed, and application thereof.
- USA, Patent No. 8,586,370(13.11.19)
Application
A novel anti-cancer fusion protein and use thereof.
- PCT No. PCT/KT2019/002531 (19.03.05)
Protein nanocage and an application thereof.
- USA, Application No. 16/247,937 (19.01.15)
- PCT No. PCT/KR2017/007679 (17.07.17)
A novel antitumor agent using exosome.
- PCT No. PCT/KR2017/015784 (17.07.17)
- USA, Application No. 16/475,052 (19.06.28)
- Japan, Application No. 2019-534796 (19.06.25)
- Europe, Application No. 17888530.7 (17.12.29)
Use of protein nanoparticle based hydrogel.
- USA, Application No. 13/938,575 (13.07.10)
Nanohair structure and an application thereof.
- USA, Application No. 14/189,552 (14.02.25)
- PCT No. PCT/KR2008/005256 (10.03.05)
Chimeric protein, method for manufacturing the same, nano-sensor in which the chimeric protein is fixed, protein is fixed, and application thereof.
- PCT No. PCT/KR2010/000640 (10.02.02)
Preparation method of recombinant protein by use a fusion expression partner.
- USA, Application No. 13/108,518 (11.05.16)
- PCT No. PCT/KR2008/005256 (08.09.05)
Domestic Patents
Registration
A novel antitumor agent using exosome.
- Patent No. 10-2129067 (20.06.25)
Protein nanocage and an application thereof.
- Patent No. 10-1953617-0000 (19.02.25)
Use of Protein nanoparticle based hydrogel.
- Patent No. 10-1721050 (17.03.23)
Protein nanoparticle based hydrogel.
- Patent No. 10-1660825 (16.09.22)
A chimeric protein, a preparation method thereof, a nanosenser fixed with the same and an application thereof.
- Patent No. 10-1309560 (13.09.11)
A chimeric protein, a preparation method thereof, a nanosenser fixed with the same and an application thereof.
- Patent No. 10-1267260 (13.05.20)
A nanohair structure and an application thereof.
- Patent No. 10-1163535 (12.07.02)
A preparation method of solubility recombinant protein by use of chemotaxis protein cheZ as a fusion expression partner.
- Patent No. 10-1077611 (11.10.21)
A preparation method of solubility recombinant protein by use of bacterioferritin as a fusion expression partner.
- Patent No. 10-1077612 (11.10.21)
A preparation method of solubility recombinant protein by use of putative HTH-type transcriptional regulator yjdC as a fusion expression partner.
- Patent No. 10-1077613 (11.10.21)
A preparation method of solubility recombinant protein by use of aspartate carbamoyl transferase catalytic chain as a fusion expression partner.
- Patent No. 10-1023518 (11.03.11)
Preparation method of recombinant protein by use of malate dehydrogenase as a fusion expression partner.
- Patent No. 10-0890183 (09.03.17)
Preparation method of recombinant protein by use of SlyD as a fusion expression partner.
- Patent No. 10-0890184 (09.03.17)
Preparation method of recombinant protein by use of Crr as a fusion expression partner.
- Patent No. 10-0890185 (09.03.17)
Preparation method of recombinant protein by use of RpoS as a fusion expression partner.
- Patent No. 10-0890186 (09.03.17)
A preparation method of solubility recombinant protein by use of Tsf as a fusion expression partner.
- Patent No. 10-0890187 (09.03.17)
A preparation method of solubility recombinant protein by use of PotD as a fusion expression partner.
- Patent No. 10-0890188 (09.03.17)
Preparation method of recombinant protein by use of RNA polymerase α subunit as a fusion expression partner.
- Patent No. 10-0890189 (09.03.17)
Application
A novel hydrogel made of functionalized Self-healing protein nanocage
- Application No. 10-2020-0165427 (20.12.01)
A novel anti-cancer fusion protein and use thereof.
- Application No. 10-2018-0026230 (18.03.06)
Protein nanocage and an application thereof.
- Application No. 10-2017-0090608 (17.07.17)
Ferritin nanocage with increased half-life.
- Application No. 10-2017-0090319 (16.07.17)
A novel antitumor agent using exosome.
- Application No. 10-2016-0182573 (16.12.29)